AIM: To prepare and submit 20ml of liquid paraffin emulsion IP.
TYPE: O/W acacia emulsion containing alcoholic liquid(biphasic liquid for Integral use)
FORMULA:
| Sl NO |
Ingredients | Official Formula |
Working Formula |
|---|---|---|---|
| 1 | Liquid Parafin | 50ml |
10ml |
| 2 | Gum Acacia |
12.5gm | 2.5gm |
| 3 | Gum Tragacanth |
0.5gm | 0.1gm |
| 4 | Sodium Benzoate | 0.5gm | 0.1gm |
| 5 | Vaniline | 0.05gm | 0.01gm |
| 6 | Glycerin | 12.5ml | 2.5ml |
| 7 | Chloroform | 0.25ml | 0.05ml |
| 8 | Purified water |
Upto 100ml |
Upto 20ml |
PRINCIPLE:
liquid paraffin is a mineral oil. Therefore 1 emulsion formula is O: W: G 3:2:1. Acacia act as an emulsifying agent; it produces O/W type emulsion syrup act as a sweetening agent, vanillin act as flavoring agent and alcohol is used to dissolve vanillin alcoholic solution should be added at the end and center of the emulsion with continuous trituration to avoid precipitation of emulsifying agent.
PROCEDURE: (Wet gum method)
- Weigh the required quantity of acacia and place it in a mortar ,add the water to produce mucilage.
- Add the calculated quantity of liquid paraffin into the mucilage and triturate vigorously to get thick creamy emulsion.
- Continue the trituration for 2-3 min to stabilize it.
- Dilute the syrup with equal quantity of water and mix it to the primary emulsion.
- Dissolve vanilline with alcohol and add this solution drop by drop to the centre of the emulsion.
- Adjust the volume with purified water, mix well.
CATEGORY: Laxative
DOSE; 30ml
LABEL: SHAKE WELL BEFORE USE.
STORAGE: In a well closed container.
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