Aim: To prepare , label and submit 30ml of liquid paraffin emulsion IP
Apparatus:
- Beaker
- Glass rod
- Measuring cylinder
- Pestle and mortar
Formula:
| Ingredients | Official Formula | Working Formula |
|---|---|---|
| Liquid Paraffin | 500ml | 15ml |
| Indian gum in powder | 125gm | 3.75gm |
| Tragacanth gum in powder | 5gm | 0.15gm |
| Sodium benzoate | 5gm | 0.15gm |
| Vanillin | 0.5gm | 0.015gm |
| Glycerin | 125gm | 3.75gm |
| Chloroform | 2.5gm | 0.075ml |
| Water up to | 1000ml | 30ml |
Principle:
This is an o/w emulsion. Liquid paraffin is a mineral oil. It is used as laxative. Acacia is used as an emulsifying agent. Gum tragacanth increases the viscosity and stabilizes emulsion. Chloroform and sodium benzoate acts as preservative. Glycerin makes the preparation viscous and adds on taste. Vanillin is a flavoring agent. Primary emulsion formula is 3:2:1 (oil: water: gum)
Procedure:
- Triturate liquid paraffin and chloroform with Indian gum, tragacanth gum and vanillin
- Add 8ml of water and triturate till a stable white primary emulsion is formed
- Add sodium benzoate and glycerin dissolved in water with trituration
- Transfer to wide mouthed bottle, make up the volume with water
- Label and dispense
Category: Laxative
Dose: 8-30ml
Storage: Store in a cool and dry place
Direction: Shake well before use.
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