Aim: To prepare and submit 1g of eutectic powder
Apparatus :
- Spatula
- Mortar & pestle
| Ingredients | Official Formula | Working Formula |
|---|---|---|
| Camphor | 5g | 50mg |
| Menthol | 5g | 50mg |
| Ammonium chloride | 30g | 300mg |
| Light magnesium carbonate | 60g | 600mg |
Principle:
Two powder when brought in physical contact with each other, if liquefies then they are called as eutectic powders. Liquefaction may be due to lowering of melting of individual solids as one substance may act as impurity to other. Examples of eutectic solids are menthol, camphor ,Thymol, salicylic acid aspirin, phenol etc.
If eutectic substance to be dispensed as powders, to prevent liquefaction diluents can be used. These diluents avoid physical contact between eutectic substances. Some commonly used diluents are light magnesium carbonate, Ammonium chloride , starch, lactose, talc, magnesium oxide etc. Alternately eutectic substances be mixed together and formed liquid can be then sorbed into suitable diluents.
Procedure:
- Mix camphor with ammonium chloride and menthol with light carbonate separately by light trituration in excess quantity
- Individual mixtures are combined together with light trituration in a mortar
- Weigh 1g of blend and pack by double wrap technique
- Dispense in a labeled envelop
- Discard the excess powder blend
Category: Nasal decongestant
Storage: Store in a cool & dry place
Direction: Used as an insufflation .
Post a Comment