Aim: To prepare, label and submit 30ml of calamine lotion I.P
Apparatus:
- Beaker
- Glass rod
- Mortal & Pestle
- Measuring cylinder
Formula:
| Ingredients | Official Formula | Working Formula |
|---|---|---|
| Calamine | 150g | 4.5g |
| Zinc oxide | 50g | 1.5g |
| Bentonite | 30g | 0.9g |
| Sodium citrate | 5g | 0.15g |
| Liquefied Phenol | 5ml | 0.15ml |
| Glycerol | 50ml | 1.5ml |
| Rose Water upto | 1000ml | 30ml |
Principle:
Lotion are liquid preparation used externally without friction. It can be solution, emulsion or suspension. They contain ingredients that are antiseptic and soothing in nature. Calamine lotion is a suspension.
Calamine is a mixture of zinc oxide with small amount of ferric oxide it serves as a antiseptic, astringent ( mild protein precipitants, which cleanse the skin, reduces oil secretion and contracts the pores) and skin protectant. Bentonite is a suspending agent. Sodium citrate is a deflocculating agent which prevents suspension from being too viscous and also prevents excessive frothing on shaking. Liquid phenol acts as antiseptic. Glycerin increases the viscosity of preparation and also acts as humectant (prevent drying up to product). Rose water serves as perfumed solvent.
Procedure:
- Triturate calamine, zinc oxide and Bentonite with solution of sodium citrate in rose water
- Add liquid phenol and glycerol to the above mixture and triturate well.
- Transfer to a clean & dry measuring cylinder make up the volume to 30ml with rose water.
- Label and dispense
Category: Skin protectant & astringent.
Label: Shake well before use for external use only
Storage: Store in a well closed container in cool place
Direction: For external use only. Shake well before use. Apply gently on affected part of body
Report: 30ml calamine lotion prepared and submited.
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